TLR10 Antikörper (Center)

Produktnummer ABIN500940

Dieses Anti-TLR10-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLR10 in WB und EIA. Geeignet für Human.

Kurzübersicht für TLR10 Antikörper (Center) (ABIN500940)

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TLR10 Antikörper

Bindungsspezifität: Center

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Ion exchange chromatography

Immunogen: TLR10 antibody was raised against a peptide corresponding to 14 amino acids near the middle of human TLR10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 to 1 μg/mL. Despite its predicted size of approx. 90 kDa, a band correpsondingto TLR10 is observed at approx. 75 kDa in immunoblot assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TLR10

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Andere Bezeichnung: CD290 / TLR10

Hintergrund: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR10 is highly homologous to TLRs 1 and 6 and is most highly expressed in lymphoid tissues (6). Most recently genetic variation in TLR10 has been associated with contributing to asthma risk (7). It should be noted that TLR10 exists in mice only as a pseudogene (8).Synonyms: Toll-like receptor 10, UNQ315/PRO358

Gen-ID: 81793

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades