Survivin Antikörper (C-Term)

Produktnummer ABIN500841

Der Kaninchen Polyklonal anti-Survivin Antikörper (ABIN500841) detektiert spezifisch Survivin in WB, IF und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Survivin Antikörper (C-Term) (ABIN500841)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Survivin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-Survivin Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects IAP4 / BIRC5 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Peptide affinity chromatography

Immunogen: Survivin antibody was raised against a peptide corresponding to amino acids near the carboxy-terminus of human survivin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 to 1 μg/mL, an approximate 17 kDa band should be detected. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Andere Bezeichnung: IAP4 / BIRC5

Hintergrund: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP (1-3). Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas (1,3).Synonyms: API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Baculoviral IAP repeat-containing protein 5, Survivin

Gen-ID: 332

NCBI Accession: NP_001159

Pathways: Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding