STEAP2 Antikörper (C-Term)

Produktnummer ABIN500821

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STEAP2 in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für STEAP2 Antikörper (C-Term) (ABIN500821)

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-STEAP2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects STEAP2 / STAMP1. It does not cross-react with other STEAP proteins.

Aufreinigung: Peptide affinity chromatography

Immunogen: STEAP2 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human STEAP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Andere Bezeichnung: STEAP2 / STAMP1

Hintergrund: The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.Synonyms: IPCA-1, IPCA1, Metalloreductase STEAP2, PCANAP1, PUMPCn, Prostate cancer-associated protein 1, Protein upregulated in metastatic prostate cancer, STEAP-2, STMP, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1

Gen-ID: 261729

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis