STEAP2 Antikörper (AA 229-258)

Produktnummer ABIN651772

Produktdetails anti-STEAP2 Antikörper

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Bindungsspezifität: AA 229-258

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STEAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-258 amino acids of human STEAP2.

Klon: RB26961

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000. WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Andere Bezeichnung: STEA2 (STEAP2 Produkte)

Synonyme: 4921538B17Rik antikoerper, AI930049 antikoerper, AW045895 antikoerper, IPCA-1 antikoerper, IPCA1 antikoerper, PCANAP1 antikoerper, STAMP1 antikoerper, STMP antikoerper, PUMPCn antikoerper, six transmembrane epithelial antigen of prostate 2 antikoerper, STEAP2 metalloreductase antikoerper, Steap2 antikoerper, STEAP2 antikoerper

Hintergrund: This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molekulargewicht: 56056

Gen-ID: 261729

NCBI Accession: NP_001035755, NP_001035756, NP_001231873, NP_001231875, NP_694544

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis