STEAP2 Antikörper (AA 400-480)

Produktnummer ABIN7209926

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch STEAP2 in IHC, ELISA, WB und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für STEAP2 Antikörper (AA 400-480) (ABIN7209926)

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-STEAP2 Antikörper

Bindungsspezifität: AA 400-480

Verwendungszweck: Rabbit Anti-STEAP2 Polyclonal Antibody

Spezifität: STEAP2 Polyclonal Antibody detects endogenous levels of STEAP2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human STEAP2 at AA range: 400-480

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:100-300,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Andere Bezeichnung: STEAP2

Hintergrund: STEAP2, PCANAP1, STAMP1, Metalloreductase STEAP2, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1STEAP2 is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molekulargewicht: 56 KD

Gen-ID: 261729

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis