STEAP2 Antikörper (AA 431-480)

Produktnummer ABIN1534012

Der Kaninchen Polyklonal anti-STEAP2 Antikörper wird verwendet zum Nachweis von STEAP2 in Proben von Human und Maus. Er wurde validiert für IHC, ELISA, WB und IF.

Kurzübersicht für STEAP2 Antikörper (AA 431-480) (ABIN1534012)

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-STEAP2 Antikörper

Bindungsspezifität: AA 431-480

Verwendungszweck: STEAP2 Antibody

Spezifität: STEAP2 Polyclonal Antibody detects endogenous levels of STEAP2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human STEA2. AA range:431-480

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Hintergrund:

Synonyms: STEAP2, PCANAP1, STAMP1, Metalloreductase STEAP2, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1

Background: STEAP2 metalloreductase(STEAP2) Homo sapiens This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: STEAP2

Protein Name: Metalloreductase STEAP2

Molekulargewicht: 55 kDa

Gen-ID: 261729

OMIM: 605094

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis