METTL7A Antikörper (C-Term)
Kurzübersicht für METTL7A Antikörper (C-Term) (ABIN500272)
Target
Alle METTL7A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody detects METTL7A C-term. It is predicted to not cross-react with MettL7B.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse
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Aufreinigung
- Peptide affinity chromatography
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Immunogen
- MettL7A antibody was raised against a 12 amino acid peptide near the carboxy terminus of human MettL7A.
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Isotyp
- IgG
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Applikationshinweise
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ELISA. Western blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- METTL7A (Methyltransferase Like 7A (METTL7A))
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Andere Bezeichnung
- METTL7A
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Hintergrund
- MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. At least two isoforms of MettL7A are known to exist.Synonyms: Methyltransferase-like protein 7A, PRO0066, UNQ1902/PRO4348
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Gen-ID
- 25840
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NCBI Accession
- NP_054752
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UniProt
- Q9H8H3
Target
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