Complement Factor B Antikörper (AA 301-400) (AbBy Fluor® 680)
Kurzübersicht für Complement Factor B Antikörper (AA 301-400) (AbBy Fluor® 680) (ABIN5002264)
Target
Alle Complement Factor B (CFB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-400
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Kreuzreaktivität
- Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Complement factor-B Bb fragment
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Isotyp
- IgG
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Applikationshinweise
- IF(IHC-P) 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Complement Factor B (CFB)
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Andere Bezeichnung
- Factor B
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Hintergrund
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Synonyms: BF, FB, BFD, GBG, CFAB, CFBD, PBF2, AHUS4, FBI12, H2-Bf, ARMD14, Complement factor B, C3/C5 convertase, Glycine-rich beta glycoprotein, Properdin factor B, CFB
Background: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
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Gen-ID
- 629
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UniProt
- P00751
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Pathways
- Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process
Target
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