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Complement C4 Antikörper (AA 701-800) (AbBy Fluor® 750)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Complement C4 in IF (p) und IF (cc). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN5000367

Kurzübersicht für Complement C4 Antikörper (AA 701-800) (AbBy Fluor® 750) (ABIN5000367)

Target

Alle Complement C4 (C4) Antikörper anzeigen
Complement C4 (C4) (Complement 4 (C4))

Reaktivität

  • 51
  • 6
  • 5
  • 1
Human

Wirt

  • 48
  • 6
  • 5
  • 3
  • 1
Kaninchen

Klonalität

  • 54
  • 9
Polyklonal

Konjugat

  • 30
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser Complement C4 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation

  • 25
  • 25
  • 19
  • 16
  • 12
  • 12
  • 10
  • 8
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • Bindungsspezifität

    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-800

    Homologie

    Human

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Complement C4 C4a anaphylatoxin or complement C4 alpha chain

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Complement C4 (C4) (Complement 4 (C4))

    Andere Bezeichnung

    Complement C4/C4

    Hintergrund

    Synonyms: C4a anaphylatoxin, Complement C4-A alpha chain, complement C4-A proprotein, Acidic C4, Acidic complement C4, Basic C4, Basic complement C4, C4 Anaphylatoxin, C4 complement C4d region, complement C4 alpha chain, C4A, C4A13, C4A2, C4A3, C4A4, C4A6, C4A91, C4B, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, C4S, CH, Chido form of C4, CO4, Complement C4 A, Complement C4 B, Complement C4B, Complement component 4A Rodgers blood group, Complement component 4A, Complement component 4B Childo blood group, Complement component 4B, Complement component C4B, CPAMD2, CPAMD3. RG, Rodgers Form Of C4.

    Background: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

    Gen-ID

    720, 721

    Pathways

    Komplementsystem
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