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c-MET Antikörper

MET Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN498617
  • Target Alle c-MET (MET) Antikörper anzeigen
    c-MET (MET) (Met Proto-Oncogene (MET))
    Reaktivität
    • 223
    • 129
    • 97
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 193
    • 38
    • 3
    • 2
    • 2
    Kaninchen
    Klonalität
    • 188
    • 50
    Polyklonal
    Konjugat
    • 126
    • 18
    • 10
    • 10
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser c-MET Antikörper ist unkonjugiert
    Applikation
    • 154
    • 96
    • 39
    • 29
    • 28
    • 20
    • 15
    • 14
    • 13
    • 8
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody detects endogenous levels of Met protein. (region surrounding Asp1228)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography using epitope-specific immunogen
    Reinheit
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product MET Primärantikörper
  • Applikationshinweise
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    c-MET (MET) (Met Proto-Oncogene (MET))
    Andere Bezeichnung
    HGF Receptor (MET Produkte)
    Hintergrund
    The c-Met oncogene was originally isolated from a chemical carcinogentreated human osteogenic sarcoma cell line by transfection analysis in NIH/ 3T3 cells. The Met proto-oncogene product was identified as a transmembrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibit transforming activity. Tyrosine phosphorylation of apparently normal Met protein has also been observed in certain human gastric carcinoma cell lines. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogenlike protein thought to be humoral mediator of liver regeneration.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met
    Molekulargewicht
    approx. 170 kDa
    Gen-ID
    4233
    NCBI Accession
    NP_000236
    UniProt
    P08581
    Pathways
    RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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