Ephrin A5 Antikörper

Produktnummer ABIN498425

Der Kaninchen Polyklonal anti-Ephrin A5 Antikörper wird verwendet zum Nachweis von Ephrin A5 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IF und IHC (p).

Kurzübersicht für Ephrin A5 Antikörper (ABIN498425)

Target: Ephrin A5 (EFNA5)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Ephrin A5 Antikörper

Spezifität: This antibody detects endogenous levels of Ephrin-A5 protein. (region surrounding Pro63)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - /200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Ephrin A5

Target: Ephrin A5 (EFNA5)

Andere Bezeichnung: Ephrin-A5

Hintergrund: Ephrin A5, a member of the ephrin family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Synonyms: AL-1, EFNA5, EPH-related receptor tyrosine kinase ligand 7, EPL7, EPLG7, LERK-7, LERK7

Molekulargewicht: approx. 25 kDa

Gen-ID: 1946

NCBI Accession: NP_001953

UniProt: P52803

Pathways: RTK Signalweg