Ephrin A5 Antikörper (AA 31-80)
Kurzübersicht für Ephrin A5 Antikörper (AA 31-80) (ABIN1533775)
Target
Alle Ephrin A5 (EFNA5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 31-80
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Verwendungszweck
- Ephrin-A5 Antibody
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Spezifität
- Ephrin-A5 Polyclonal Antibody detects endogenous levels of Ephrin-A5 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human EFNA5. AA range:31-80
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Ephrin A5 (EFNA5)
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Andere Bezeichnung
- EFNA5
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Hintergrund
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Synonyms: EFNA5, EPLG7, LERK7, Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, LERK-7
Background: Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divi
Gene Name: EFNA5
Protein Name: Ephrin-A5
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Molekulargewicht
- 26 kDa
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Gen-ID
- 1946
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OMIM
- 601535
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UniProt
- P52803
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Pathways
- RTK Signalweg
Target
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