CSNK1A1 Antikörper

Produktnummer ABIN498265

Produktdetails anti-CSNK1A1 Antikörper

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSNK1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Casein Kinase I α protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Andere Bezeichnung: Casein Kinase I alpha (CSNK1A1 Produkte)

Synonyme: CK1 antikoerper, CK1a antikoerper, CKIa antikoerper, HLCDGP1 antikoerper, PRO2975 antikoerper, 2610208K14Rik antikoerper, 4632404G05Rik antikoerper, 5430427P18Rik antikoerper, Csnk1a antikoerper, CHUNP6894 antikoerper, ck1alpha antikoerper, wu:fb65a02 antikoerper, wu:fi30h04 antikoerper, wu:fj19c11 antikoerper, zgc:92158 antikoerper, KER1 antikoerper, ck1 antikoerper, CKIALPHA antikoerper, CK-II antikoerper, CSNK2A1 antikoerper, CG2028 antikoerper, CK I antikoerper, CK1alpha antikoerper, CKI antikoerper, CKI alpha antikoerper, CKIalpha antikoerper, CkIa antikoerper, Dmel\\CG2028 antikoerper, PKA-C antikoerper, anon-WO03040301.93 antikoerper, anon-WO03040301.95 antikoerper, ck1a antikoerper, dmCK1 antikoerper, dmckI antikoerper, l(1)G0492 antikoerper, casein kinase 1 alpha 1 antikoerper, casein kinase 1, alpha 1 antikoerper, keratin 1 antikoerper, casein kinase 1 alpha 1 L homeolog antikoerper, casein kinase 2 alpha 1 antikoerper, Casein kinase Ialpha antikoerper, CSNK1A1 antikoerper, Csnk1a1 antikoerper, csnk1a1 antikoerper, KRT1 antikoerper, csnk1a1.L antikoerper, CSNK2A1 antikoerper, CkIalpha antikoerper

Hintergrund: Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Iε, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.Synonyms: CK1, CKI-alpha, CSNK1A1

Molekulargewicht: approx. 35 kDa

Gen-ID: 1452

NCBI Accession: NP_001883

UniProt: P48729

Pathways: WNT Signalweg, Hedgehog Signalweg