CSNK1A1 Antikörper (pTyr294)
Kurzübersicht für CSNK1A1 Antikörper (pTyr294) (ABIN6256701)
Target
Alle CSNK1A1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr294
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Spezifität
- Phospho-CK-1 alpha (Tyr294) Antibody detects endogenous levels of CK-1 alpha only when phosphorylated at PhoTyr294
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Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human Phospho-CK-1 alpha (Tyr294)
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-3000 IHC 1:200, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
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Andere Bezeichnung
- CK-1 alpha
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Hintergrund
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Description: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).
Gene: CSNK1A1
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Molekulargewicht
- 38 kDa
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Gen-ID
- 1452
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UniProt
- P48729, Q8N752
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Pathways
- WNT Signalweg, Hedgehog Signalweg
Target
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