TLR2 Antikörper (AA 212-242)

Produktnummer ABIN3029164

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLR2 in WB, IHC, FACS und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TLR2 Antikörper (AA 212-242) (ABIN3029164)

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Produktdetails anti-TLR2 Antikörper

Bindungsspezifität: AA 212-242

Kreuzreaktivität (Details): Expected species reactivity: Primate

Aufreinigung: Purified

Immunogen: A portion of amino acids 212-242 from the human protein was used as the immunogen for this TLR2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TLR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TLR2

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Andere Bezeichnung: TLR2

Hintergrund: TLR2 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. [UniProt]

UniProt: O60603

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades