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Src Antikörper (AA 24-52)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Src in WB, ELISA, IHC, IF und FACS. Er zeigt eine Reaktivität gegenüber Human.

Src antibody western blot analysis in (1) MCF-7 and (2) A431 lysate (Src Antikörper (AA 24-52))

Confocal immunofluorescent analysis of Src antibody with MCF-7 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Src Antikörper (AA 24-52))

Src antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue (Src Antikörper (AA 24-52))

Src antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human small intestine tissue (Src Antikörper (AA 24-52))

Confocal immunofluorescent analysis of Src antibody with A431 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Src Antikörper (AA 24-52))

Src antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue (Src Antikörper (AA 24-52))

Confocal immunofluorescent analysis of Src antibody with MCF-7 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Src Antikörper (AA 24-52))

Confocal immunofluorescent analysis of Src antibody with A431 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Src Antikörper (AA 24-52))

Src antibody flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control (left histogram). (Src Antikörper (AA 24-52))

Src antibody western blot analysis in (1) MCF-7 and (2) A431 lysate (Src Antikörper (AA 24-52))

10 Abbildungen

Produktnummer ABIN3029554

Kurzübersicht für Src Antikörper (AA 24-52) (ABIN3029554)

Target

Alle Src Antikörper anzeigen

Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Reaktivität

225
142
131
10
9
7
5
5
5
4
4
2
1
1
1

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

130
18
15
12
9
7
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3

Dieser Src Antikörper ist unkonjugiert

Applikation

189
119
70
55
53
34
34
27
24
12
11
9
4
3
3
1

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Discover our top product Src Primärantikörper

Bindungsspezifität
25

23

20

20

15

15

15

12

10

8

7

6

4

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 24-52

Kreuzreaktivität (Details)

Expected species reactivity: Mouse

Aufreinigung

Antigen affinity purified

Immunogen

A portion of amino acids 24-52 from the human protein was used as the immunogen for this Src antibody.

Isotyp

Ig Fraction
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
Src Reaktivität: Human, Maus WB, IF Wirt: Maus Monoclonal 17AT28 unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52), (N-Term) antibody
Src Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB41141 unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
Src Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 1F11 unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 1-80) antibody
Src Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr530) antibody
Src Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
KO Validated Src Reaktivität: Human WB, IF, IP Wirt: Kaninchen Monoclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 397-424) antibody
Src Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr529) antibody
Src Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 397-424) antibody
Src Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB21492 unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 1-90) antibody
Src Reaktivität: Human WB, ELISA, IF, IHC (p), PLA Wirt: Maus Monoclonal 1B9 unconjugated

Applikationshinweise

Titration of the Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000,IHC (Paraffin): 1:50,Flow Cytometry: 1:50,Immunofluorescence: 1:50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Aliquot the Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target

Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Andere Bezeichnung

Src

Hintergrund

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-Src kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

UniProt

P12931

Pathways

JAK-STAT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling

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