PRDM2 Antikörper (AA 1-347)

Produktnummer ABIN3032300

Der Maus Monoklonal Anti-PRDM2-Antikörper wurde für WB, ELISA und ChIP validiert. Er ist geeignet, PRDM2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für PRDM2 Antikörper (AA 1-347) (ABIN3032300)

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRDM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)

Klon: 33AT1045

Produktdetails anti-PRDM2 Antikörper

Bindungsspezifität: AA 1-347

Aufreinigung: Purified

Immunogen: Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This RIZ1 antibody is specific and does not recognize the beta isoform (RIZ2).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Titration of the RIZ1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,ChIP: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RIZ1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PRDM2

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Andere Bezeichnung: RIZ1

Hintergrund: This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q13029