PRDM2 Antikörper (AA 245-573)

Produktnummer ABIN356710

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRDM2 in WB, IP, IHC (p) und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PRDM2 Antikörper (AA 245-573) (ABIN356710)

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PRDM2 Antikörper

Bindungsspezifität: AA 245-573

Spezifität: This antibody also recognizes the isoform beta (Riz2) of PRDM2 (185 kDa)

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: Purified recombinant GST fusion protein encoding aa 245-573 of Rat Riz1. Genename: PRDM2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot.1/100-1/500. Immunohistochemistry: 1/100-1/500. Immunoprecipitation: 1 μg Pab/100 μg cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu PRDM2

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Andere Bezeichnung: PRDM2

Hintergrund: PRDM2 is a 250-kD nuclear protein containing 8 zinc finger motifs. It contains an RB-binding motif that is related to that of the adenovirus E1A oncoprotein, RIZ also shares an antigenic epitope with the C terminus of E1A. It is expressed in human retinoblastoma cells and at low levels in all other human cell lines examined. Using fluorescence in situ hybridization, the PRDM2 gene has been mapped to 1p36. PRDM2 may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, skin, and lymphoid tumors.Synonyms: GATA-3-binding protein G3B, HUMHOXY1, KMT8, Lysine N-methyltransferase 8, MTB-ZF, MTE-binding protein, PR domain zinc finger protein 2, RIZ1, RIZ2, Retinoblastoma protein-interacting zinc finger protein

Gen-ID: 7799, 5874

UniProt: Q13029