PRDM2 Antikörper (AA 50-150)

Produktnummer ABIN6146141

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRDM2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PRDM2 Antikörper (AA 50-150) (ABIN6146141)

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PRDM2 Antikörper

Bindungsspezifität: AA 50-150

Sequenz: ILKGKKFGPF VGDKKKRSQV KNNVYMWEVY YPNLGWMCID ATDPEKGNWL RYVNWACSGE EQNLFPLEIN RAIYYKTLKP IAPGEELLVW YNGEDNPEIA A

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PRDM2 (NP_036363.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PRDM2

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Andere Bezeichnung: PRDM2

Hintergrund: This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.,PRDM2,HUMHOXY1,KMT8,KMT8A,MTB-ZF,RIZ,RIZ1,RIZ2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Nuclear Receptor Signaling,Cancer,Tumor suppressors,Neuroscience,PRDM2

Molekulargewicht: 25 kDa/162 kDa/166 kDa/184 kDa/188 kDa

Gen-ID: 7799

UniProt: Q13029