PKM2 Antikörper (AA 121-151)

Produktnummer ABIN3032418

Produktdetails anti-PKM2 Antikörper

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Bindungsspezifität: AA 121-151

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Rabbit, Rat

Aufreinigung: Purified

Immunogen: A portion of amino acids 121-151 from the human protein was used as the immunogen for this Pyruvate Kinase antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Pyruvate Kinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Pyruvate Kinase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PKM2

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Andere Bezeichnung: Pyruvate Kinase (PKM2) (PKM2 Produkte)

Hintergrund: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

UniProt: P14618

Pathways: Warburg Effekt