CDK2 Antikörper (pThr14)
Kurzübersicht für CDK2 Antikörper (pThr14) (ABIN3030608)
Target
Alle CDK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pThr14
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Verwendungszweck
- Phospho-CDK2 Antibody (pT14)
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Bovine, Hamster, Xenopus
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Aufreinigung
- Antigen affinity
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Immunogen
- This phospho-CDK2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT14 of human CDK2.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the phospho-CDK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the phospho-CDK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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Andere Bezeichnung
- CDK2
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Hintergrund
- CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.
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UniProt
- P24941
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Pathways
- PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
Target
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