PDK4 Antikörper

Produktnummer ABIN3028962

Der Maus Monoklonal anti-PDK4 Antikörper (Klon 345CT19-6-2) (ABIN3028962) detektiert spezifisch PDK4 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PDK4 Antikörper (ABIN3028962)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 345CT19-6-2

Produktdetails anti-PDK4 Antikörper

Aufreinigung: Purified

Immunogen: A purified His-tagged recombinant protein fragment was used to produced this monoclonal PDK4 antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Andere Bezeichnung: PDK4

Hintergrund: This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

UniProt: Q16654

Pathways: PI3K-Akt Signalweg, Hedgehog Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt