PCNA Antikörper (AA 231-261)
Kurzübersicht für PCNA Antikörper (AA 231-261) (ABIN3032321)
Target
Alle PCNA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 231-261
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Kreuzreaktivität (Details)
- Expected species reactivity: Rat, Bovine, Primate, Hamster
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 231-261 from the human protein was used as the immunogen for this PCNA antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the PCNA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the PCNA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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Andere Bezeichnung
- PCNA
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Hintergrund
- PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. This protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.
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UniProt
- P12004
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Pathways
- Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie
Target
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