PCNA Antikörper (AA 236-261)
Kurzübersicht für PCNA Antikörper (AA 236-261) (ABIN3032323)
Target
Alle PCNA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 236-261
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Verwendungszweck
- PCNA Antibody (Proliferating Cell Nuclear Antigen)
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Kreuzreaktivität (Details)
- Expected species reactivity: Bovine, Primate, Hamster
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 236-261 from human Proliferating Cell Nuclear Antigen was used as the immunogen for this PCNA antibody.
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Isotyp
- IgG1
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Applikationshinweise
- Titration of the PCNA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the PCNA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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Andere Bezeichnung
- PCNA
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Hintergrund
- This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
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UniProt
- P12004
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Pathways
- Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie
Target
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