PARP1
Reaktivität: Human
WB, 2D-PAGE
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Titration of the PARP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the PARP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
PARP1
(Poly (ADP-Ribose) Polymerase 1 (PARP1))
Andere Bezeichnung
PARP
Hintergrund
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. It is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. [UniProt]