SQSTM1 Antikörper (pSer403)
Kurzübersicht für SQSTM1 Antikörper (pSer403) (ABIN3031542)
Target
Alle SQSTM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer403
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
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Aufreinigung
- Antigen affinity purified
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Immunogen
- This p-p62 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS403 of human p62/SQSTM1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the p-p62 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the p-p62 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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Andere Bezeichnung
- p62 SQSTM1
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Hintergrund
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
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UniProt
- Q13501
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Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
Target
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