NEU1 Antikörper (AA 188-214)
Kurzübersicht für NEU1 Antikörper (AA 188-214) (ABIN3032558)
Target
Alle NEU1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 188-214
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Verwendungszweck
- NEU1 Antibody / Sialidase-1
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Kreuzreaktivität (Details)
- Expected species reactivity: Bovine
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 188-214 from the human protein was used as the immunogen for this NEU1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the NEU1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the NEU1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
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Andere Bezeichnung
- NEU1
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Hintergrund
- The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
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UniProt
- Q99519
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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