NEU1 Antikörper (Middle Region)

Produktnummer ABIN2781801

Produktdetails anti-NEU1 Antikörper

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEU1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VWSKDDGVSW STPRNLSLDI GTEVFAPGPG SGIQKQREPR KGRLIVCGHG

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NEU1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NEU1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 415 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NEU1

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Andere Bezeichnung: NEU1 (NEU1 Produkte)

Synonyme: NANH antikoerper, NEU antikoerper, SIAL1 antikoerper, MGC81958 antikoerper, AA407268 antikoerper, AA407316 antikoerper, Aglp antikoerper, Apl antikoerper, Bat-7 antikoerper, Bat7 antikoerper, G9 antikoerper, Map-2 antikoerper, Neu antikoerper, Neu-1 antikoerper, neuraminidase 1 antikoerper, neuraminidase 1 (lysosomal sialidase) L homeolog antikoerper, NEU1 antikoerper, neu1.L antikoerper, neu1 antikoerper, Neu1 antikoerper

Hintergrund: NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.
Alias Symbols: NEU, SIAL1, NANH
Protein Interaction Partner: FBXO6, JUNB, LIG4, KCNA4, KCNA2, UBC, HDAC5, CTSA, GLB1, EEF1A1, GALNS,
Protein Size: 415

Molekulargewicht: 45 kDa

Gen-ID: 4758

NCBI Accession: NM_000434, NP_000425

UniProt: Q99519

Pathways: SARS-CoV-2 Protein Interaktom