NEU1 Antikörper (AA 188-214)

Produktnummer ABIN3032558

Produktdetails anti-NEU1 Antikörper

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Bindungsspezifität: AA 188-214

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEU1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Bovine

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 188-214 from the human protein was used as the immunogen for this NEU1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NEU1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NEU1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NEU1

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Andere Bezeichnung: NEU1 (NEU1 Produkte)

Hintergrund: The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.

UniProt: Q99519

Pathways: SARS-CoV-2 Protein Interaktom