MECP2 Antikörper (AA 58-87)
Kurzübersicht für MECP2 Antikörper (AA 58-87) (ABIN3031763)
Target
Alle MECP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 58-87
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Verwendungszweck
- MeCP2 Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Primate
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.
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Isotyp
- Ig Fraction
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anti-Methyl CpG Binding Protein 2 (MECP2) (AA 7-148) antibody
MECP2 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 8H4A5B9 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibodyMECP2 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1B11 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (pSer423) antibodyMECP2 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB29261 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) antibodyMECP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 400-428) antibodyMECP2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB25959 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (C-Term) antibodyMECP2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 58-87), (N-Term) antibodyMECP2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB27934 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibodyMECP2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal 4B6 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (N-Term) antibodyMECP2 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-100) antibodyMECP2 Reaktivität: Human IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Titration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the MeCP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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Andere Bezeichnung
- MeCP2
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Hintergrund
- MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]
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UniProt
- P51608
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Pathways
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
Target
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