IRAK1 Antikörper (AA 405-433)
Kurzübersicht für IRAK1 Antikörper (AA 405-433) (ABIN3028764)
Target
Alle IRAK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 405-433
-
Verwendungszweck
- Irak1 Antibody
-
Aufreinigung
- Antigen affinity
-
Immunogen
- A portion of amino acids 405-433 from the mouse protein was used as the immunogen for this Irak1 antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the Irak1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the Irak1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
-
Andere Bezeichnung
- Irak1
-
Hintergrund
- Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.
-
UniProt
- Q62406
-
Pathways
- NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Target
-