Glucagon Antikörper (AA 119-148)

Produktnummer ABIN3031052

Der Maus Monoklonal Anti-Glucagon-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Glucagon in Proben von Human zu detektieren.

Kurzübersicht für Glucagon Antikörper (AA 119-148) (ABIN3031052)

Target: Glucagon (GCG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glucagon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 329CT36-10-10

Produktdetails anti-Glucagon Antikörper

Bindungsspezifität: AA 119-148

Aufreinigung: Purified

Immunogen: A portion of amino acids 119-148 from the human protein was used as the immunogen for this Glucagon antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Titration of the Glucagon antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Glucagon antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Glucagon

Target: Glucagon (GCG)

Andere Bezeichnung: Glucagon

Hintergrund: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

UniProt: P01275

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling