E2F1 Antikörper (AA 342-371)
Kurzübersicht für E2F1 Antikörper (AA 342-371) (ABIN3030786)
Target
Alle E2F1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 342-371
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 342-371 from the human protein was used as the immunogen for this E2F1 antibody.
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Isotyp
- Ig Fraction
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anti-E2F Transcription Factor 1 (E2F1) (AA 69-223) antibody
E2F1 Reaktivität: Human, Maus WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 8G9 unconjugated
anti-E2F Transcription Factor 1 (E2F1) antibodyE2F1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Monoclonal 1D12 unconjugated Recombinant Antibody
anti-E2F Transcription Factor 1 (E2F1) (AA 348-437) antibodyE2F1 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 2E10 unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 133-362) antibodyE2F1 Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 101-180) antibodyE2F1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (p), IF (cc), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibodyE2F1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB7913 unconjugated
anti-E2F Transcription Factor 1 (E2F1) antibodyE2F1 Reaktivität: Human WB, IF, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibodyE2F1 Reaktivität: Human WB, ELISA, FACS, IF (p), IF (cc), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (pThr433) antibodyE2F1 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (C-Term) antibodyE2F1 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Titration of the E2F1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the E2F1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- E2F1 (E2F Transcription Factor 1 (E2F1))
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Andere Bezeichnung
- E2F1
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Hintergrund
- E2F1 is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters. [UniProt]
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UniProt
- Q01094
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Pathways
- p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
Target
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