BAX Antikörper (AA 41-76)
Kurzübersicht für BAX Antikörper (AA 41-76) (ABIN3030145)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 41-76
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Kreuzreaktivität (Details)
- Expected species reactivity: Bovine
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 41-76 (BH3 domain) from the human protein was used as the immunogen for this Bax antibody.
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Isotyp
- Ig Fraction
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anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Huhn, Zebrafisch (Danio rerio) WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibodyBAX Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB0952 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reaktivität: Human, Maus, Ratte, Affe, Schwein, Rind (Kuh), Kaninchen, Hund, Huhn, Schaf, Pferd, Meerschweinchen, Ziege, Hamster, Avian, Cat, Esel WB, IF Wirt: Ziege Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibodyBAX Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibodyBAX Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 4H9B11 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 2G6B2 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 2D8H2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibodyBAX Reaktivität: Human WB, ELISA, IF, IHC (p), PLA Wirt: Maus Monoclonal 1F5-1B7 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reaktivität: Human, Schwein, Rind (Kuh), Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Titration of the Bax antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Bax antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- Bax
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Hintergrund
- Bax belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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