BAX Antikörper (N-Term)
Kurzübersicht für BAX Antikörper (N-Term) (ABIN3030141)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 47-78, N-Term
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Verwendungszweck
- BAX Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- This BAX antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 47-78 amino acids from the N-terminal region of human BAX.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the BAX antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the BAX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- BAX
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Hintergrund
- Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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