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Caspase 3 Antikörper (AA 60-90)

Dieses Anti-Caspase 3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Caspase 3 in WB, IHC, ELISA und FACS. Geeignet für Human.
Produktnummer ABIN3030306

Kurzübersicht für Caspase 3 Antikörper (AA 60-90) (ABIN3030306)

Target

Alle Caspase 3 (CASP3) Antikörper anzeigen
Caspase 3 (CASP3)

Reaktivität

  • 219
  • 129
  • 86
  • 18
  • 11
  • 8
  • 8
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 244
  • 30
  • 3
  • 2
  • 2
Kaninchen

Klonalität

  • 224
  • 56
Polyklonal

Konjugat

  • 177
  • 22
  • 21
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser Caspase 3 Antikörper ist unkonjugiert

Applikation

  • 215
  • 135
  • 100
  • 64
  • 61
  • 55
  • 49
  • 37
  • 29
  • 27
  • 25
  • 10
  • 10
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 29
    • 16
    • 16
    • 14
    • 12
    • 12
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-90

    Aufreinigung

    Purified

    Immunogen

    A portion of amino acids 60-90 from the human protein was used as the immunogen for this anti-Caspase-3 antibody.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Titration of the anti-Caspase-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the anti-Caspase-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Caspase 3 (CASP3)

    Andere Bezeichnung

    Caspase-3

    Hintergrund

    CASP3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

    UniProt

    P42574

    Pathways

    Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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