NLRP12 Antikörper

Produktnummer ABIN3032018

Der Maus Monoklonal anti-NLRP12 Antikörper wird verwendet zum Nachweis von NLRP12 in Proben von Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für NLRP12 Antikörper (ABIN3032018)

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NLRP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 228CT4-1-3

Produktdetails anti-NLRP12 Antikörper

Aufreinigung: Purified

Immunogen: This NALP12 antibody was produced from a mouse immunized with NLRP12/NALP12 recombinant protein.

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the NALP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C for up to one month. For long term, aliquot the NALP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Andere Bezeichnung: NALP12 (NLRP12)

Hintergrund: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome