The stated application concentrations are suggested starting amounts. Titration of the CHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at 4°C for up to one month. For long term, aliquot the CHK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Andere Bezeichnung
CHK1
Hintergrund
Checkpoint kinase 1, commonly referred to as CHK1 is an serine/threonine-specific protein kinase that in humans, is encoded by the CHEK1 gene. CHK1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. Activation results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death to prevent damaged cells from progressing through the cell cycle.