Calnexin Antikörper
Kurzübersicht für Calnexin Antikörper (ABIN4949485)
Target
Alle Calnexin (CANX) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- Calnexin Antibody (azide and preservative free)
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Keine Kreuzreaktivität
- Ratte (Rattus)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Titering of the Calnexin antibody may be required for optimal performance.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Calnexin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Calnexin (CANX)
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Andere Bezeichnung
- Calnexin
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Hintergrund
- It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
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UniProt
- P27824
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Pathways
- MAPK Signalweg, Thyroid Hormone Synthesis
Target
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