Calnexin Antikörper

Produktnummer ABIN4949485

Der Maus Monoklonal Anti-Calnexin-Antikörper wurde für WB, ELISA, IHC (p) und IF/ICC validiert. Er ist geeignet, Calnexin in Proben von Human zu detektieren.

Kurzübersicht für Calnexin Antikörper (ABIN4949485)

Target: Calnexin (CANX)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (fixed cells) (IF/ICC)

Klon: CANX-1541

Produktdetails anti-Calnexin Antikörper

Keine Kreuzreaktivität: Ratte (Rattus)

Aufreinigung: Protein G affinity chromatography

Immunogen: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Titering of the Calnexin antibody may be required for optimal performance.\. ELISA: 2-4 μg/mL (order BSA-free format for coating),WB: 1-2 μg/mL,IF/ICC: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Calnexin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: Calnexin

Hintergrund: It recognizes a protein of 90  kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis