Complement Factor H Antikörper

Produktnummer ABIN492503

Produktdetails anti-Complement Factor H Antikörper

Target: Complement Factor H (CFH)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Complement Factor H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: Clone OX-24 inhibits the binding of factor H to surface bound C3. This antibody recognizes the Human serum complement protein factor H and a 43-49 kDa truncated form of factor H.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: CFH, HF, HF1, HF2, H factor 1

Aufreinigung: Protein G Chromatography.

Immunogen: Purified Human complement factor H protein

Klon: OX-24

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot. Immunoprecipitation. Flow Cytometry. Immunohistochemistry on Paraffin Sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Complement Factor H

Target: Complement Factor H (CFH)

Abstract: CFH Produkte

Hintergrund: Factor H (CFH) is a protein with twenty short consensus repeat (SCR) domains. Factor H is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in Factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2

Gen-ID: 3075

UniProt: P08603

Pathways: Komplementsystem, Cellular Response to Molecule of Bacterial Origin