BAX Antikörper

Produktnummer ABIN4901053

Dieses Maus Monoklonal-Antikörper erkennt spezifisch BAX in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Affe.

Kurzübersicht für BAX Antikörper (ABIN4901053)

Target: BAX (BCL2-Associated X Protein (BAX))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BAX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 2B12-G6-H6

Produktdetails anti-BAX Antikörper

Verwendungszweck: Mouse monoclonal to Bax.

Spezifität: This antibody detects endogenous levels of Bax and does not cross-react with related proteins.

Produktmerkmale: Mouse Monoclonal to Bax.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Purified recombinant human Bax protein fragments expressed in E.coli

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000
ELISA 1:10000-20000

Kommentare:

Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin. Isoform Alpha and isoform Sigma are expressed in pro-myelocytic leukemia, histiocytic lymphoma, Burkitt's lymphoma, T-cell lymphoma, lymphoblastic leukemia, breast adenocarcinoma, ovary adenocarcinoma, prostate carcinoma, prostate adenocarcinoma, lung carcinoma, epidermoid carcinoma, small cell lung carcinoma and colon adenocarcinoma cell lines.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu BAX

Target: BAX (BCL2-Associated X Protein (BAX))

Andere Bezeichnung: Bax

Molekulargewicht: 20kDa

Gen-ID: 581

UniProt: Q07812

Pathways: p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response