ATG5 Antikörper

Produktnummer ABIN4901026

Dieses Maus Monoklonal-Antikörper erkennt spezifisch ATG5 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ATG5 Antikörper (ABIN4901026)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ATG5 Antikörper

Verwendungszweck: ATG5 is a protein encoded by the ATG5 gene which is approximately 32,4 kDa. ATG5 is localised to the cytoplasm. It is involved in the autophagy pathway, longevity regulating pathway, the innate immune system and pink/parkin mediated mitophagy. It functions as an E1-like activating enzyme, in combination with autophagy protein 12, in a ubiquitin-like conjugating system. It is involved in multiple cellular processes such as mitochondrial quality control after oxidative damage, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. ATG5 is expressed ubiquitously in human tissues and mutations in the ATG5 gene may result in Bardet-Biedl syndrome. STJ98903 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous ATG5 protein.

Spezifität: The antibody detects endogenous ATG5 protein.

Produktmerkmale: Mouse Monoclonal to ATG5.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant peptide derived from ATG5.

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000
ELISA 1:10000-20000

Kommentare:

Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Andere Bezeichnung: ATG5

Molekulargewicht: 55kDa

Gen-ID: 9474

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagie