IRF9 Antikörper (AA 1-110)

Produktnummer ABIN4886637

Dieses Anti-IRF9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IRF9 in WB. Geeignet für Human.

Kurzübersicht für IRF9 Antikörper (AA 1-110) (ABIN4886637)

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRF9 Antikörper

Bindungsspezifität: AA 1-110

Verwendungszweck: Anti-Interferon regulatory factor 9/IRF9 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Interferon regulatory factor 9/IRF9 Antibody Picoband® (ABIN4886637). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human IRF9 recombinant protein (Position: M1-K110). Human IRF9 shares 87.3% amino acid (aa) sequence identity with mouse IRF9.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human
1. Fu, X.-Y., Kessler, D. S., Veals, S. A., Levy, D. E., Darnell, J. E., Jr. ISGF3, the transcriptional activator induced by interferon alpha consists of multiple interacting polypeptide chains. Proc. Nat. Acad. Sci. 87: 8555-8559, 1990. 2. Levy, D. E., Kessler, D. S., Pine, R., Darnell, J. E., Jr. Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro. 3. Suhara, W., Yoneyama, M., Yonekawa, H., Fujita, T. Structure of mouse interferon stimulated gene factor 3 gamma (ISGF3 gamma/p48) cDNA and chromosomal localization of the gene. J. Biochem. 119: 231-234, 1996.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu IRF9

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Andere Bezeichnung: IRF9

Hintergrund:

Synonyms: Interferon regulatory factor 9,IRF-9,IFN-alpha-responsive transcription factor subunit,ISGF3 p48 subunit,Interferon-stimulated gene factor 3 gamma,ISGF-3 gamma,Transcriptional regulator ISGF3 subunit gamma,IRF9,ISGF3G,

Tissue Specificity: Leukocytes.

Background: Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G. It is mapped to 14q1. IRF9 is a 48 kDa member of the IRF family of proteins. It is widely expressed, and serves as a component of the ISGF3 complex. In addition, IRF9 is an interferon-dependent, positive-acting transcription factor that is cytoplasmically activated, possibly through interaction with the interferon receptor. It associates with activated STAT1 and STAT2 to form an ISGF3 complex that is translocated into the nucleus.

Molekulargewicht: 44 kDa

Gen-ID: 10379

UniProt: Q00978

Pathways: JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C