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FSHR Antikörper (AA 18-187)

Dieses Anti-FSHR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FSHR in WB. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN4886595

Kurzübersicht für FSHR Antikörper (AA 18-187) (ABIN4886595)

Target

Alle FSHR Antikörper anzeigen
FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Reaktivität

  • 97
  • 51
  • 50
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 78
  • 22
Kaninchen

Klonalität

  • 78
  • 21
  • 1
Polyklonal

Konjugat

  • 41
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FSHR Antikörper ist unkonjugiert

Applikation

  • 59
  • 46
  • 29
  • 26
  • 26
  • 22
  • 15
  • 13
  • 10
  • 10
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 16
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-187

    Verwendungszweck

    Anti-FSH Receptor/FSHR Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-FSH Receptor/FSHR Antibody Picoband® (ABIN4886595). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived human FSH Receptor recombinant protein (Position: C18-N187). Human FSH Receptor shares 91.2% and 90% amino acid (aa) sequence identity with mouse and rat FSH Receptor, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Gromoll, J., Ried, T., Holtgreve-Grez, H., Nieschlag, E., Gudermann, T. Localization of the human FSH receptor to chromosome 2p21 using a genomic probe comprising exon 10. J. Molec. Endocr. 12: 265-271, 1994.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Wu, Shi, Gong, Yu, Chen, Wang, Sun: "Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127595, (2016) (PubMed).

  • Target

    FSHR (Follicle Stimulating Hormone Receptor (FSHR))

    Andere Bezeichnung

    FSHR

    Hintergrund

    Synonyms: Follicle-stimulating hormone receptor,FSH-R,Follitropin receptor,FSHR,LGR1,

    Tissue Specificity: Sertoli cells and ovarian granulosa cells.

    Background: The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). This FSHR gene is mapped to chromosome 2p21 by fluorescence in situ hybridization. The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.

    Molekulargewicht

    78 kDa

    Gen-ID

    2492

    UniProt

    P23945

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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