SMPD3 Antikörper

Produktnummer ABIN4620370

Der Kaninchen Polyklonal anti-SMPD3 Antikörper wird verwendet zum Nachweis von SMPD3 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für SMPD3 Antikörper (ABIN4620370)

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMPD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMPD3 Antikörper

Spezifität: This antibody detects Sphingomyelin Phosphodiesterase 3, predominantly expressed in the brain.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide derived from human sphingomyelin phosphodiesterase 3

Anwendungsinformationen

Applikationshinweise: Western blot (1: 400 starting dilution). Protein appears to run lower than expected proteinmolecular weight. However, antibody is specific for the protein and band blocks whenblocking peptide used.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Details zu SMPD3

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Andere Bezeichnung: SMPD3

Hintergrund: Sphingomyelin phosphodiesterase 3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these two cellular events independently. It also hydrolyzes sphingosylphosphocholine. Sphingomyelin phosphodiesterase 3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It likely acts as a regulator of postnatal development and participates in bone and dentin mineralization. It is activated by unsaturated fatty acids and phosphatidylserine. it is predominantly expressed in the brain.Synonyms: Neutral sphingomyelinase 2, Neutral sphingomyelinase II, Sphingomyelin phosphodiesterase 3

Gen-ID: 55512

NCBI Accession: NP_061137

UniProt: Q9NY59

Pathways: Hormone Transport