SMPD3 Antikörper

Produktnummer ABIN635767

Produktdetails anti-SMPD3 Antikörper

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMPD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purified

Immunogen: SMPD3 antibody was raised using a synthetic peptide corresponding to a region with amino acids RPPEADDPVPGGQARNGAGGGPRGQTPNHNQQDGDSGSLGSPSASRESLV

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

SMPD3 Blocking Peptide, catalog no. 33R-8099, is also available for use as a blocking control in assays to test for specificity of this SMPD3 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SMPD3 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu SMPD3

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Andere Bezeichnung: SMPD3 (SMPD3 Produkte)

Synonyme: 4631433G07Rik antikoerper, AI427456 antikoerper, AW537966 antikoerper, fro antikoerper, nSMase2 antikoerper, cca1 antikoerper, NSMASE2 antikoerper, sphingomyelin phosphodiesterase 3 antikoerper, sphingomyelin phosphodiesterase 3, neutral antikoerper, SMPD3 antikoerper, Smpd3 antikoerper

Hintergrund: SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Molekulargewicht: 71 kDa (MW of target protein)

Pathways: Hormone Transport