Caspase 1 Antikörper

Produktnummer ABIN461892

Produktdetails anti-Caspase 1 Antikörper

Target: Caspase 1 (CASP1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Aufreinigung: Immunoaffinity purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, IHC, IHC-P (5 μg/mL), WB (0.5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. Western Blot: Casp-1 antibody can be used for the detection of Caspase-1 by Western blot at 0.5 μg/mL. Depending on cell lines or tissues used, other cleavage products may be observed.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles. Store undiluted.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Caspase 1

Target: Caspase 1 (CASP1)

Andere Bezeichnung: CASP1 / Caspase 1 (CASP1 Produkte)

Synonyme: ICE antikoerper, IL1BC antikoerper, P45 antikoerper, Il1bc antikoerper, Ice antikoerper, CASP1 antikoerper, CG5370 antikoerper, DCP-1 antikoerper, DCP1 antikoerper, Dcp1 antikoerper, Dmel\\CG5370 antikoerper, ccp1 antikoerper, dcp-1 antikoerper, dcp1 antikoerper, l(2)01862 antikoerper, l(2)02132 antikoerper, caspase 1 antikoerper, caspase 1, apoptosis-related cysteine peptidase antikoerper, caspase 4, apoptosis-related cysteine peptidase antikoerper, Death caspase-1 antikoerper, caspase-1 antikoerper, caspase antikoerper, caspase recruitment domain-containing protein 16 antikoerper, caspase 4 antikoerper, CASP1 antikoerper, Casp1 antikoerper, CASP4 antikoerper, Dcp-1 antikoerper, Caspase1 antikoerper, LOC5564196 antikoerper, LOC451519 antikoerper

Hintergrund: Name/Gene ID: CASP1
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP1, Caspase-1, CASP-1, CASP1 nirs variant 1, Caspase 1, ICE, ICE-like protease, IL-1 beta-converting enzyme, IL-1BC, IL1BC, IL1BCE, p45, IL1B-convertase, Interleukin-1 beta convertase

Gen-ID: 834

UniProt: P29466

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome