STAT5B Antikörper (pThr694)

Produktnummer ABIN452651

Der Maus Monoklonal Anti-STAT5B-Antikörper wurde für EIA validiert. Er ist geeignet, STAT5B in Proben von Human zu detektieren.

Kurzübersicht für STAT5B Antikörper (pThr694) (ABIN452651)

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser STAT5B Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: A2H6

Produktdetails anti-STAT5B Antikörper

Bindungsspezifität: pThr694

Spezifität: Reactive to Tyrosine 699 phosphorlylated human STAT5b peptide fragment conjugated with KLH or the peptide-BSA conjugate, but not reactive to unconjugated KLH or BSA.

Produktmerkmale: Synonyms: STAT-5B, Signal transducer and activator of transcription 5B

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Peptide of a phosphorlylated fragment of STAT5b (p-T694), conjugated with KLH

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Indirect ELISA: The suggested antigen coating quantity is 1 μg/mL of peptide/or peptideconjugating in pH 9.5 carbonate buffer, 100 μL/well .
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu STAT5B

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Andere Bezeichnung: STAT5B

Hintergrund: Stat5b is a transcription factor that is activated in response to extra-cellular stimuli including IL-2, IL-4, MCSF and a variety of growth factors. In the process, receptor associated kinases phosphorylate Stat5b. Stat5b, then, forms dimers and translocates to nucleus. Inside nucleus, Stat5b binds to the promoter region on various genes to regulate biological processes such as apoptosis, T cell receptor signalling, and adult mammary gland development. Fusion of Stat5b to retinoic acid receptor-alpha (RARα) gene was identified in a small subgroup of acute promyelocytic leukemia patients.Synonyms: STAT-5B, Signal transducer and activator of transcription 5B

Gen-ID: 6777

UniProt: P51692

Pathways: JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation