ELK1 Antikörper (pSer383)

Produktnummer ABIN452642

Der Maus Monoklonal Anti-ELK1-Antikörper wurde für EIA validiert. Er ist geeignet, ELK1 in Proben von Human zu detektieren.

Kurzübersicht für ELK1 Antikörper (pSer383) (ABIN452642)

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ELK1 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: D7H2

Produktdetails anti-ELK1 Antikörper

Bindungsspezifität: pSer383

Spezifität: Reactive to the un-conjugated serine383 phosphorylated Human ELK-1 peptide fragment, and reactive to the Serine383 phosphorylated Human ELK-1 peptide fragment conjugated to KLH or the peptide- BSA conjugate.Not reactive to KLH or BSA.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: Elk-1, ETS domain-containing protein Elk-1

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Peptide of a phosphorylated fragment of ELK1 (pSer383) conjugated with KLH.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Indirect ELISA: The suggested antigen Coating quantity is 1 μg/mL of peptide/or peptideconjugating in pH 9.5 carbonate buffer, 100 μL/well.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.0 without preservatives

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu ELK1

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Andere Bezeichnung: ELK1

Hintergrund: ELK1 belongs to the EST transcription factor family. Proteins in the family have a unique DNA binding domain that binds to conserved DNA sequences. Phosphorylation of ELK1 at serine 383 and 389 by mitogen-activated protein kinases (MAPKs) activates ELK1. The binding of ELK1 to target sequences is also regulated by its co-factor, serum response factor (SRF), by alternative splicing, and by SUMOylation. ELK1 regulates the transcription of c-fos and genes encoding cytoskeleton proteins, and was found to play a role in longterm memory formation, drug addiction and other neurological disorders.Synonyms: ETS domain-containing protein Elk-1, Elk-1

Gen-ID: 2002

UniProt: P19419

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling